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01 — 22 Applied Biosciences  ·  Public Investor Deck

ABx

Build the wedge. Earn the platform.

Seed Round 2026 $12M Applied Genomics
02

Overview

ABx is building a sequenced applied-biology company with a clearly bounded first market. Mino is the initial commercial wedge: premium companion-animal offerings organized around defined product boundaries, disciplined delivery, and a customer category with adjacent demand but no trusted leader. Companion animals come first because that market offers a narrower commercial and regulatory wedge than direct livestock deployment.

If that first wedge validates demand, trust, and regulatory sequencing, the same platform may later support welfare-oriented applications in livestock. The argument of this deck is therefore sequential rather than speculative: establish a credible entry point first, then evaluate broader welfare applications on stronger technical and institutional footing.1, 2, 4, 6, 7, 22

03 Problem

The tools exist. The category does not.

Gene editing has already moved from basic research into regulated commercial use in animals and medicine.6, 7, 22 Yet companion animals still have no trusted category owner even though adjacent buyers already pay for cloning, selective breeding, and specialty care inside a $158B U.S. pet market.16, 18, 21

ABx starts with that narrower commercial gap. The broader welfare thesis matters because more than 90 billion land animals are slaughtered each year for food,19 most in intensive systems,20 but the first market still has to be built where demand, trust, and regulation are easiest to sequence.

90B+ Animals raised & slaughtered
annually worldwide19
$158B U.S. pet industry spend in 202516
95M U.S. households owning at least one pet in 202521
04 Thesis
A companion-animal business can finance a broader welfare platform.

ABx operates through two linked programs. Mino is the near-term commercial wedge: premium companion-animal offerings where consumers already pay for bespoke biology through cloning, selective breeding, and specialty care.18, 21 The longer-horizon program applies the same technical platform to pain-pathway modification in livestock.5, 9 The relationship is practical rather than rhetorical: the companion market can produce revenue, regulatory experience, and genotype-to-phenotype data that de-risk a larger welfare agenda.

Large-capital biology platforms validate investor appetite for ambitious biotech. None is organized around this market sequence.

05 Product
Mino

Specified before they exist.

Mino is the first public commercial wedge. Initial commercialization focuses on premium, high-trust traits that can be described clearly to customers and eventually defended to regulators: coat, size, temperament, allergen profile, and longevity. The longer design space is broader, but the first market does not require maximal novelty; it requires credible delivery.

  • Coat & colour
  • Size
  • Allergen profile
  • Temperament
  • Longevity
  • Longer-horizon novel traits
mino.xtcftw.com — Join the waitlist →
06 Technical Basis

The enabling stack is no longer hypothetical.

GalSafe

FDA-approved gene-edited pig. Alpha-gal sugar knocked out via intentional genomic alteration. Approved for both food and potential xenotransplantation use. December 2020.6

FDA, Revivicor / United Therapeutics
PRLR-SLICK

Heat-tolerant cattle produced via CRISPR modification of the prolactin receptor gene. FDA enforcement discretion granted March 2022 — the first for gene-edited livestock.7

FDA, Acceligen / Recombinetics
241M+

AlphaFold DB v6 now contains more than 241 million predicted protein structures, and AlphaFold 3 extended prediction from proteins alone to protein, DNA, RNA, ligand, and complex interactions in 2024.4

EMBL-EBI / Google DeepMind
Cost curve

NHGRI's long-run sequencing-cost series shows a multi-order-of-magnitude drop since 2001, with the curve breaking sharply away from Moore's law once next-generation sequencing arrived in 2008.3

NHGRI
Pig Kidney

Massachusetts General Hospital performed the world's first gene-edited pig kidney transplant into a living human in March 2024 and a second living-recipient kidney xenotransplant in January 2025.8

MGH / Mass General Brigham
Casgevy

Casgevy became the first FDA-approved therapy to use CRISPR/Cas9 in December 2023, making genome editing a regulated therapeutic reality rather than a research-only technique.22

FDA / Vertex / CRISPR Therapeutics
07 Timing

Cost, design, and delivery curves have shifted.

Moore+

NHGRI's benchmark shows genome sequencing costs outpaced Moore's law after 2008 and have stayed on a sharply downward curve ever since.3

NHGRI
241M

AlphaFold DB v6 has moved structural lookup from scarcity to abundance, with more than 241 million predicted protein structures now openly available.4

EMBL-EBI / DeepMind
CRISPR drug

The first FDA-approved CRISPR/Cas9 therapy arrived in December 2023. Editing has now crossed from platform promise into commercial medicine.22

FDA
No leader

No scaled company has yet defined the product boundaries, trust model, and regulatory sequencing for a companion-animal wedge. The capability stack exists, but the category still has to be earned.

Commercial landscape review
08 Execution Model

Specify. Sequence. Deliver.

I

Screen

Customer requests are screened for biological plausibility, welfare constraints, and regulatory tractability. The early product is a constrained design brief, not unrestricted trait selection.

II

Engineer

Programs advance only through a narrow intervention plan, full quality control, and welfare review before any case moves forward.1 The operational discipline is closer to regulated biotech than luxury breeding.

III

Deliver

Licensed partner facilities handle gestation, veterinary oversight, and delivery. ABx retains the genomic workflow, post-delivery monitoring, and the outcome dataset that improves future programs.

09 Regulatory Path

Precedent exists, but the product path still has to be earned.

FDA / US Explicit framework. FDA's 2024 guidance refresh keeps heritable intentional genomic alterations inside a defined drug-style review framework. Full NADA review remains long, but the review architecture is explicit and already has public animal precedents in GalSafe pigs and PRLR-SLICK cattle.6, 7, 23 That matters because the category is legible, not because ABx's exact path is already settled.
Argentina Flexible treatment. Argentina's Resolution 173/2015 created a case-by-case path for crops developed with modern biotechnology to fall outside GMO treatment when no new combination of genetic material is present. It is a strong precedent for trait-based gene-editing treatment, but the original framework was agricultural rather than a direct companion-animal route.13
Japan Commercial precedent. Notification-based treatment for gene-edited organisms without transgene insertion has already supported commercialized edited fish. It provides a concrete reference point for non-US sequencing.14
UK / EU context Policy movement. England's 2025 Precision Breeding Regulations operationalize the Act, but the Food Standards Agency still says there are currently no crops or animals resulting from precision breeding technology authorised for sale as food or feed in the UK. The policy direction is moving, but no market precedent exists yet.15
Launch logic Parallel, not single-market. ABx is not dependent on a single-market launch. The operating assumption is early work in jurisdictions with clearer treatment of precision-bred edits, while the US remains a strategic but parallel track. The objective is to establish precedent methodically rather than assume a one-shot approval path.
10 Market Entry

Pick the first reference market, not the whole map.

ABx does not need global approval to prove the category. The first job is to launch where premium demand, veterinary mediation, and regulatory legibility overlap tightly enough to create first precedent.

Priority 01

Asia Pacific

Japan already offers a notification path for gene-edited products. Japan, Singapore, and South Korea create the cleanest first-adopter wedge for a tightly scoped premium launch.

Why it fits Fast precedent + premium pet spend
Priority 02

GCC

The GCC already supports concierge veterinary care and status-linked companion spending. This is a premium trust market, not a mass-market pet channel.

Why it fits High-discretionary buyers + mediated care
Priority 03

European Union

Europe is slower, but welfare framing may resonate more clearly there than in a pure consumer-biotech pitch. One approval can still create a multi-country signal.

Why it fits Welfare-led review can create durable trust

Launch rule: establish one reference market, then compound from precedent.

Sources 14, 15, 16, 18

11 Demand & Economics

Demand is visible before the category exists.

ABx is not underwriting all pets. It is targeting a premium, high-trust segment inside a category where owners already pay emotionally, repeatedly, and at luxury-biotech price points.

Installed spend $152B

Current demand already exists.

U.S. pet spend reached $152B in 2024 across a 94M-household ownership base. ABx only needs a narrow premium segment inside that installed demand.

Observed willingness to pay $50K

Luxury-biotech spend is real.

Pet cloning already proves that a subset of owners will pay biotech prices for identity-linked outcomes and continuity.

Category ownership Open

No brand owns the trust model yet.

No scaled company has set the product boundaries, launch sequence, or customer expectations for companion genomics.

ABx does not need mainstream adoption. It needs the first premium trust model.

Sources 16, 18, 21

12 Competitive Landscape

Adjacent companies prove fragments of the thesis.

Incumbents validate capital appetite, technical infrastructure, or buyer willingness to pay. None define a companion-animal wedge with defined product boundaries and a welfare-aware frame.

Biology is already funded.

Luxury spend in pets is already proven.

Category ownership is still open.

ABx / Mino

Companion-animal wedge

Owns the public wedge, defined offer, and welfare-aware category frame.

No other company combines all three.

ViaGen Pets

Luxury biotech spend

Shows that owners already pay biotech prices for identity and continuity.

Does not own trait design, category rules, or a welfare mandate.

Ginkgo Bioworks

Cell programming infrastructure

Proves platform-level biology infrastructure can attract capital and enterprise demand.

Not a consumer animal category and not a trust brand.

Genus / PIC

Animal genetics at scale

Shows that animal genetics can become a serious commercial operating system.

No premium pet wedge, no consumer surface, no welfare narrative.

Colossal Biosciences

Ambitious biology attracts capital

Large-scale biotech storytelling can pull attention and capital into frontier biology.

Not a companion-animal commercialization sequence.

Source anchor 18

13 Defensibility

The moat compounds with every governed delivery.

01

Category Definition

Set the acceptable trait set, language, and care model first.

Later entrants inherit the frame.

02

Regulatory Precedent

One recognized path becomes the benchmark for later review.

Later filings cite the first win.

03

Proprietary Data

Each delivery sharpens genotype-to-phenotype screening.

Design quality improves with use.

04

Welfare Governance

Explicit rules make the category legible to buyers and regulators.

Trust compounds only with limits.

ABx wins by becoming the reference system, not by running a louder marketing race.

14 Business Model

Revenue turns on as proof clears.

Each layer activates after a narrower hurdle is cleared. The model is sequential by design: prove trust, then unlock higher-value revenue.

01 Reservation $250–$2.5K

Qualified deposits only after delivery timing becomes credible.

Gate: signal quality + timing proof.

02 Delivery $15K–$75K

Initial commercial delivery in a tightly scoped premium market.

Gate: regulatory path + partner-lab readiness.

03 Subscription $200 / mo

Monitoring, health data, and lifetime service attached to the animal.

Gate: first animals in market.

04 Licensing Fees + royalty

Protocol licensing and facility partners once the playbook is repeatable.

Gate: validated operating system.

15 Progress

Current work is proof gathering, not theater.

ABx is pre-revenue and pre-lab by design. The present job is to collect demand, regulatory, and hiring signals before capital is deployed into scientific execution.

Live now

Waitlist live

Mino is public and already capturing language, buyer, and interest-quality signals ahead of commercialization.

Regulatory map drafted

Relevant animal-editing precedents are already sequenced into a multi-jurisdiction launch thesis.

Sources 6, 7, 14, 15, 23

In build

Scientific advisory capacity

Early conversations are underway with gene-editing and animal-genomics operators who can own quality thresholds.

Demand validation

Pricing, objections, and psychographic fit are being tested through waitlist behavior and direct outreach.

16 Roadmap

Seed capital buys the first chain of proof.

Each milestone narrows risk before the next one opens. The roadmap is built to create precedent, not to simulate scale too early.

Q3 2026

Seed Close

Recruit scientific and regulatory leadership and lock the first lab plan.

2027

Platform Validation

Run early editing workflows through partner facilities and build the first safety dataset.

2028

First Filings

Advance tightly scoped dossiers and turn qualified demand into a regulated pipeline.

2029–2030

Initial Delivery

Execute the first commercial deliveries in a narrow reference market with veterinary oversight.

2031–2034

Data Expansion

Deepen the genotype-to-phenotype layer and widen the operating network.

2034+

Livestock Extension

Open only after the companion-animal platform has earned technical and regulatory credibility.

Livestock work remains downstream of companion proof.

17 Long-Horizon Extension

Pain-pathway editing is legible, but it is not the seed wedge.

The commercial thesis stands on companion animals first. The livestock program matters later because one narrow pain pathway already has a coherent mechanistic literature.

Target

SCN9A / Nav1.7

Loss-of-function evidence links the channel directly to pain signalling, making the biology unusually legible.

Circuit framing

ACC

The affective component of pain can be reasoned about separately from protective reflexes.

Why it matters

Single-locus tractability

This is narrower and more mechanistically legible than most animal-welfare ideas, even if translation remains far away.

Constraint

No commercial market yet

The ethical case is mature. The governed commercialization path still does not exist.

Sources 5, 9, 10, 11, 12

18 Founder & Team Buildout

Operator in seat. Scientific leadership is the seed unlock.

The raise does not fund a sprawling org chart. It installs the minimum leadership needed to turn a category thesis into governed execution.

Current mandate

Define the first market, product boundaries, and launch sequence for a category with no standard template.

Current work

Run the seed process, refine the waitlist and product brief, and recruit scientific ownership early.

Raise unlock

Scientific leadership, regulatory ownership, partner-lab capacity, and the first governed validation data.

Founder role

Category design, capital formation, product framing, and early sequencing across research, brand, and launch.

Open role · Scientific co-founder

Deep gene-editing or animal-genomics operator who can own experimental design, quality thresholds, and partner-lab decisions.

Open role · Regulatory lead

FDA CVM or comparable animal-biotech operator who can own sequencing, dossier strategy, and jurisdiction design.

19 Execution Risks

The principal risks are explicit.

Off-target edits Risk: CRISPR-class systems can introduce off-target events. Mitigation: Initial programs are expected to use narrower edit classes, conservative advancement criteria, and full-genome quality control before gestation proceeds.1
Regulatory timeline Risk: No jurisdiction has yet approved a gene-edited companion animal for commercial sale. Mitigation: ABx assumes a multi-jurisdiction strategy rather than a US-only sequence, with the raise structured around that longer path.15, 23
Consumer acceptance Risk: The category requires unusually high trust. Mitigation: The initial trait set is intentionally limited, veterinary oversight is integral, and the product must be explained in a way that is legible to both regulators and buyers.
Solo founder Risk: Scientific and regulatory leadership still need to be recruited. Mitigation: The seed raise is structured around hiring those roles early because category creation without that leadership would be governance failure.
20 Capital

$12M

Seed Round · 2026

ABx is raising $12M to recruit the scientific and regulatory core team, secure BSL-2+ lab capacity, generate initial validation data, and advance the first jurisdictional submissions. The near-term objective is not global scale; it is early precedent in a category that still has no established leader. Capital is therefore being applied to the team and the first regulated proof points, rather than to premature scale.

Target close: Q3 2026
First filing path: 2028
Open to strategic breeders and biotech LPs
Use of Funds
Lab Buildout
40%
Regulatory Framework
30%
3 Pilot Deliveries
20%
Platform & Engineering
10%
21 References

Sources & citations.

[1] Jinek, M. et al. "A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity." Science 337, 816-821 (2012).
[2] FDA. "FDA Approves First Gene Therapies to Treat Patients with Sickle Cell Disease." December 8, 2023. Casgevy is the first FDA-approved therapy to use CRISPR/Cas9.
[3] NHGRI. DNA Sequencing Costs: Data. Updated May 16, 2023. Used for the long-run sequencing cost-collapse curve and the Moore's-law comparison.
[4] EMBL-EBI / PDBe. AlphaFold Database v6 release notes (2025): 241,070,489 predicted protein structures. DeepMind's AlphaFold 3 paper in Nature (2024) extended prediction to biomolecular complexes.
[5] Cox, J.J. et al. "An SCN9A channelopathy causes congenital inability to experience pain." Nature 444, 894-898 (2006).
[6] FDA. Approval of GalSafe pigs (Revivicor). Intentional Genomic Alteration. December 14, 2020.
[7] FDA. Enforcement discretion for PRLR-SLICK cattle (Acceligen / Recombinetics). March 2022.
[8] Massachusetts General Hospital / Mass General Brigham. World's first gene-edited pig kidney transplant into a living recipient (March 2024) and second living-recipient transplant (January 2025).
[9] Shriver, A. "Knocking out pain in livestock: Can technology succeed where morality has stalled?" Neuroethics 2, 115-124 (2009).
[10] Pain behavior in SCN9A (Nav1.7) and SCN10A mutant rodent models. Neuroscience & Biobehavioral Reviews (2021). Used for the preclinical Nav1.7 knockout literature.
[11] Pearce, D. The Hedonistic Imperative (1995). Used for the welfare-maximization framing.
[12] Singer, P. Animal Liberation (1975). Used for the moral baseline on farmed-animal suffering.
[13] Argentina Ministry of Agriculture. Resolution 173/2015: non-GMO treatment for some gene-edited organisms without foreign DNA.
[14] Japan Ministry of Health. Gene-edited food notification framework (2019). Madai sea bream and tiger puffer used as commercialization precedents.
[15] Food Standards Agency; GOV.UK Precision Breeding Register. England's 2025 Precision Breeding Regulations are in force, but only precision-bred plants can currently be released or marketed and no animals are yet authorized for food or feed.
[16] APPA 2026 State of the Industry release (March 26, 2026). U.S. pet industry expenditures reached $158 billion in 2025.
[17] APPA 2026 State of the Industry release (March 26, 2026). APPA reported 71 million U.S. dog-owning households and 53 million cat-owning households in 2025.
[18] ViaGen Pets veterinarian page (accessed April 2026). Current listed cloning prices: dog $50,000 and cat $50,000; ViaGen also reports more than 500 veterinary-network members.
[19] FAOSTAT / Our World in Data. Latest land-animal slaughter series places the global total above 90 billion animals per year.
[20] Our World in Data / Sentience Institute. Factory-farming estimates used for the intensive-systems framing in the welfare slide.
[21] APPA 2026 State of the Industry release (March 26, 2026). 95 million U.S. households owned at least one pet in 2025.
[22] FDA. Casgevy approval history. First FDA-approved therapy utilizing CRISPR/Cas9 genome editing.
[23] FDA. "FDA Clarifies Approach to Genomic Alterations in Animals." May 1, 2024. Final GFI #187A and draft revised GFI #187B.
22

What should a welfare-first
biology company build first?